27–31 Oct 2025
InterContinental Chengdu Global Center
Asia/Shanghai timezone
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Status of AGOR accelerator facility at Particle Therapy Research Center in Groningen, Netherlands

WEBI01
29 Oct 2025, 10:30
30m
InterContinental Chengdu Global Center

InterContinental Chengdu Global Center

Chengdu, China
Invited Oral Presentation Operation and Upgrades Cyclotron Applications (4)

Speaker

Herman Kremers (Particle Therapy Research Center)

Description

PARticle Therapy REsearch Center (PARTREC) operates the AGOR AVF superconducting cyclotron capable of delivering multiple particle types (protons, light and heavy ions) at multiple extraction energies (from 8 to 190 MeV/u, dependent on particle type).

Following decades of routine operation of AGOR’s cryogenic system, the filling of the cryostat and extraction channels with liquid helium became increasingly unstable. This greatly impeded AGOR’s ability to reliably deliver ion beams and eventually resulted in a prolonged technical shutdown of the facility. A comprehensive cryogenic system overhaul has further enhanced operational stability. The many lessons learned during this exercise will be presented.

Recent upgrades have significantly expanded PARTREC’s capabilities. The new EMC1 extraction element has demonstrated reliable operation. High-intensity beam development (>1 μA) now supports both FLASH radiotherapy and the production of theranostic radioisotopes, notably Terbium. Dedicated dosimetry monitors have been developed to ensure precise dose delivery at ultra-high dose rates. Advancements in ion source technology now allow fine control of proton beam intensity and the inclusion of xenon in the heavy ion cocktail, contributing to more efficient radiation hardness testing. These developments position PARTREC as a unique multidisciplinary hub for cutting-edge research in particle therapy, radiobiology, and nuclear science.

Author

Brian Jones (Particle Therapy Research Center)

Co-authors

Sytze Brandenburg (Particle Therapy Research Center) Dr Marc-Jan van Goethem (Particle Therapy Research Center) Mr Jan de Jong (Particle Therapy Research Center) Herman Kremers (Particle Therapy Research Center) Jacobus Schippers (Particle Therapy Research Center) Alexander Gerbershagen (Particle Therapy Research Center)

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