17–22 May 2026
C.I.D
Europe/Zurich timezone

Optimized design of a C-band 100 MeV electron LINAC for FLASH radiotherapy

TUP3071
19 May 2026, 16:00
2h
C.I.D

C.I.D

Deauville, France
Poster Presentation MC3.T02: Advanced techniques/Novel sources: Electron Sources Poster session

Speaker

Stefano Farina (Sapienza University of Rome)

Description

Electron LINACs are key tools for radiotherapy. Conventional low-energy ones can treat only superficial tumors. Achieving Very High Energy Electrons (VHEE, >100 MeV) enables treatment of deep-seated tumors. Furthermore, electrons are well-suited for delivering Ultra-High Dose Rates (UHDR) required for FLASH therapy, which improves healthy-tissue sparing. Combining VHEE and FLASH in a hospital environment represents an important step forward for Radiotherapy.
In the context of the SAFEST project at Sapienza, this work presents a compact and cost-effective accelerator layout capable of delivering hundreds of nC at 100 MeV within tens of pulses over 1 ms of irradiation. The design emphasizes efficient RF power usage through high-efficiency C-band structures and a pulse compressor. Beam dynamics simulations and low-power RF tests validate the approach. A strong focus is placed on flattening the compressor signal, which must remain stable over 1 mus to accommodate electrons from a triode thermionic gun, a compact and economical source for this accelerator. The resulting 3-m linac, powered by a single 20-MW klystron, shows strong potential for future hospital-based FLASH VHEE treatments.

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Author

Stefano Farina (Sapienza University of Rome)

Co-authors

Alessandro Curcio (Sapienza University of Rome) Prof. Alessio Sarti (Sapienza University of Rome) Andrea Mostacci (Sapienza University of Rome) David Alesini (Istituto Nazionale di Fisica Nucleare) Enrica Chiadroni (Sapienza University of Rome) Fabio Cardelli (Istituto Nazionale di Fisica Nucleare) Dr Gaia Francosioni (Sapienza University of Rome) Dr Giorgio Mauro (Istituto Nazionale di Fisica Nucleare) Giuseppe Torrisi (Istituto Nazionale di Fisica Nucleare) Ms Laura Frassi (Sapienza University of Rome) Dr Luca Ficcadenti (Istituto Nazionale di Fisica Nucleare, Sezione di Roma I) Lucia Giuliano (Sapienza University of Rome) Luigi Faillace (Istituto Nazionale di Fisica Nucleare) Luigi Palumbo (Sapienza University of Rome) Mr Marco Magi (Sapienza University of Rome) Mr Massimiliano Coppola (Sapienza University of Rome) Mauro Migliorati (Istituto Nazionale di Fisica Nucleare) Riccardo Boldrini (Sapienza University of Rome) Shoaib Akbar (Sapienza University of Rome) Prof. Vincenzo Patera (Sapienza University of Rome)

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