Speaker
Description
Very High Energy Electron (VHEE) beams offer a promising tool to achieving FLASH dose rates for deep-seated tumour irradiation. To investigate these parameters, zebrafish embryos (ZFE) were used as sensitive biodosimeters and were irradiated with VHEE beams delivered by the CERN Linear Electron Accelerator for Research (CLEAR). The CLEAR facility enables precise modulation of beam timing by adjusting the dose in each bunch and the number of bunches per train, allowing controlled variations of average dose rate and bunch-level dose delivery. Recent measurements show that the FLASH effect depends primarily on the instantaneous dose rate and is independent of the overall irradiation time. These findings have important implications for the design of future VHEE treatment facilities.
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