19–24 May 2024
Music City Center
US/Central timezone

Nozzle design optimization for proton FLASH therapy

THPR50
23 May 2024, 16:00
2h
Rock 'n Roll (MCC Exhibit Hall A)

Rock 'n Roll

MCC Exhibit Hall A

Poster Presentation MC8.A28 Medical Applications Thursday Poster Session

Speaker

Georgios Kourkafas (Helmholtz-Zentrum Berlin für Materialien und Energie)

Description

An increasing number of accelerators are pursuing FLASH radiotherapy, which promises to mitigate unwanted damage to healthy tissues by applying ultra-high dose rates. To reach this extreme intensity regime, it is necessary to maximize the transmission through the exit nozzle, apart from increasing the accelerator’s output beam current. Simultaneously, the delivered beam properties must satisfy certain quality criteria that clinical applications require, such as transverse homogeneity.
For this reason, a Python-based software has been developed to optimize the design of double-scattering beam nozzles. For a user-defined set of incoming beam parameters, output field requirements and available materials, the tool searches for the most efficient scattering conditions utilizing a graphical interface. These conditions are then translated into distances and shaping of the scatterers, involving a combination of high and low-density elements in a multiple-ring arrangement. A solution for the treatment of eye tumors has been successfully calculated, implemented, and tested with beam, in order to demonstrate the capabilities of this approach.

Region represented Europe
Paper preparation format LaTeX

Primary author

Georgios Kourkafas (Helmholtz-Zentrum Berlin für Materialien und Energie)

Co-authors

Andrea Denker (Helmholtz-Zentrum Berlin für Materialien und Energie) Andreas Weber (Charité - Universitätsmedizin Berlin) Jens Heufelder (Charité - Universitätsmedizin Berlin) João Paulo Lima (Helmholtz-Zentrum Berlin für Materialien und Energie)

Presentation materials

There are no materials yet.