1–6 Jun 2025
Taipei International Convention Center (TICC)
Asia/Taipei timezone

Installation, operation, and upgrade of a CS-30 cyclotron for the production of alpha emitters At-211 and Ac-225 at the Ionetix TAT facility

TUPB048
3 Jun 2025, 16:00
2h
Exhibiton Hall A _Bear (TWTC)

Exhibiton Hall A _Bear

TWTC

Poster Presentation MC8.U04 Isotope Production Tuesday Poster Session

Speaker

Xiaoyu Wu (Ionetix Corporation)

Description

Ionetix Corporation has been conducting research and development on compact superconducting cyclotrons for medical isotope production, with multiple Ion-12SC units installed and operated at customer sites in USA. Since 2021, we have also focused on the production of alpha-emitting medical isotopes for cancer therapy, specifically At-211 and Ac-225. As a first step, Ionetix acquired an existing, partial CS-30 Cyclotron system decommissioned and stored in a warehouse. We refurbished and upgraded the CS-30 cyclotron, replacing components as needed. The installation of the CS-30 was completed in 2022, and it has been operational, accelerating alpha and proton beams since 2023. The refurbished cyclotron features new main and trim coils, a new internal bismuth target and drive, and a new central region to enhance the beam-on-target performance. All power supplies, controls, and instrumentation were replaced with commercially available components. The first production of At-211 at Ionetix was achieved in April 2023, followed by the first production of Ac-225 in June 2024. This paper analyzes and describes the CS-30 cyclotron, and the upgrades and enhancements developed at Ionetix.

Region represented America
Paper preparation format Word

Author

Xiaoyu Wu (Ionetix Corporation)

Co-authors

Brandon McLean (Ionetix Corporation) Gabe Blosser (Ionetix Corporation) Gary Horner (Ionetix Corporation) John Vincent (Ionetix Corporation) Nathan Usher (Ionetix Corporation) Rick Hart (Ionetix Corporation) Sergey Vorozhtsov (Joint Institute for Nuclear Research) Victor Smirnov (Joint Institute for Nuclear Research) Zachary Neville (Ionetix Corporation)

Presentation materials

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